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Home / MCNTalk / What's in a Name? For Illnesses, it's Fodder for Debate

March 9, 2011

What’s in a Name? For Illnesses, it’s Fodder for Debate

A study of chronic fatigue syndrome, published last month in The Lancet, has highlighted how competing case definitions for illnesses and syndromes can lead to confusion rather than clarification — what you see depends on who’s doing the looking — and has stoked a fierce debate among researchers and patient advocates on both sides of the Atlantic as noted in this New York Times article.

“If you recognize something is happening, you need a case definition so you can count it,” said Andrew Moss, an emeritus professor of epidemiology at U. C. San Francisco and an early AIDS investigator. “You need to know whether the numbers are going up or down, or whether treatment and prevention work. And if you have a bad case definition, then it’s very difficult to figure out what’s going on.”

Once a disease can be diagnosed reliably through lab tests, creating an accurate case definition becomes easier. But when an ailment has no known cause and its symptoms are subjective — as with chronic fatigue syndrome, fibromyalgia, and other diseases whose characteristics and even existence have been contested — competing case definitions are almost inevitable.

What does this mean for the patient? Well, quite a lot. As the article notes, treatments could easily vary depending upon which diagnostic measurements a physician were using. In the case of chronic fatigue, some researchers believe that the syndrome is  a psychological condition and patients would benefit from exercise. Other researchers, however, are deeply convinced it is a viral disease and note that the exercise therapy advised by the Lancet study can cause major relapses in people with chronic fatigue syndrome — a claim supported by some patient surveys. Read more…

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Tagged: Clinical Issues, Research Report, Sociology and Language of Medicine, The Practice of Medicine 1 Comment

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  1. Kirmach Natani, Ph.D. says

    March 12, 2011 at 7:43 am

    I agree. The DSM is notorious for descriptions of symptoms that cvan be applied to a number of maladies. ADHD is one example. Back in the 1950s when we had Minimal Brain Dysfunction as a diagnosis it was recognizd that this problem was characterized by behaviors that have now been attributed to ADHD. It has apparently been forgotten that these symptoms are common to all types of brain damage and as such represent a biomarker for brain damage per se which can include the sequele of hypoxic stress, malnutrition, fetal alcohol exposure, metabolic syndromes, and epilepsy. All of which, now, thanks to the DSM are most likely to be treated under the rubric of ADHD or the latest diagnostic fad for children, BiPolar disorder. This need not continue since there are tests test, which the DSM never identifies or recommends, available. A series of congenital abnormalities of the head and face can flag risk of schizophrenia in children, sophisticated quantitative EEG tests can tease out fetal alcohol exposure, autism, and epilepsy. Four of the 5 most common neurodevelopmental disorders have seizures as a common feature. There is also a graphic biomarker for fetal alcohol exposure that has been around since Alfred Binet published his first scale but it’s use has been neglected. New directions are definitely needed in this area so that clients can be treated for what is actually wrong with them instead of, in the case of a seizure related attention problem, being treated with stimulants that may make their condition worse.

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